Let me be very honest with you.
Every year, thousands of JAMB candidates score well, sometimes very well, and still don’t get admission. Not because they failed. Not because they didn’t try hard enough. But because they made one silent, painful mistake during registration;
They chose the wrong JAMB subject combinations.
It’s one of those mistakes you don’t notice immediately. You write JAMB, you celebrate your score, you buy Post-UTME forms… and then boom, “You are not eligible for this course.”
That’s heartbreaking.
This mega guide on JAMB Subject Combinations for All Courses was created to make sure that doesn’t happen to you.
In this article, you’ll learn:
- What JAMB subject combinations really means (in simple terms)
- Why one wrong subject can ruin your admission chances
- The correct JAMB subject combination for all major courses
- Faculty-by-faculty breakdowns (Science, Arts, Business, Medical, etc.)
- Common mistakes students keep repeating every year
- Practical tips to double-check your choices before submission
If you’re serious about gaining admission, read this guide slowly. Bookmark it. Share it. Come back to it before you submit your JAMB form.
What Is JAMB Subject Combinations?
JAMB subject combinations simply refers to the four subjects you register for and write in the UTME.
Here’s the golden rule you must never forget:
Use of English is compulsory for all courses. No exceptions.
That means you don’t “choose” English, it’s automatically included.
The real decision is about the other three subjects, and those three must match:
- Your chosen course
- JAMB’s official requirements
- The requirements of the universities, polytechnics, or colleges you’re applying to
Think of your subject combinations like a key.
If the key doesn’t fit the course, the admission door will not open, no matter how high your JAMB score is.
Read also: WAEC Subject Combinations 2026: Official Full List, Admission Tips & Expert Advice
Why Choosing the Right Subject Combinations Is Extremely Important
Some students treat subject combination like a minor detail.
It is not.
Here’s why it matters more than many people realize:
1. JAMB Uses It to Filter Candidates Automatically
Before any school even looks at your score, JAMB already knows whether you’re eligible or not eligible based on your subjects.
2. Schools Use It During Screening
During Post-UTME or admission screening, schools cross-check:
- Your UTME subjects
- Your O’Level subjects
- Your intended course
One mismatch, and you’re screened out quietly.
3. High Score + Wrong Subjects = Zero Admission
You can score 280 and still lose admission to someone with 210 who chose the correct subjects.
Painful, but true.
General Rules for JAMB Subject Combinations (Read This Carefully)
Before we dive into individual courses, you need to understand these general rules:
- English Language is compulsory for all courses
- Science courses usually require: Mathematics, At least two core science subjects
- Business courses almost always require: Mathematics, Economics
- Arts courses usually require: Literature, Government, History, CRS/IRS, or related subjects
- Some courses are flexible, others are very strict
Now let’s break everything down properly.
JAMB Subject Combinations for Medical and Health-Related Courses
Medical and health courses are among the strictest when it comes to subject combinations. There’s little to no flexibility here.
Medicine and Surgery (MBBS)
- Use of English
- Biology
- Chemistry
- Physics
This combination is non-negotiable. No Mathematics replacement. No Economics. Nothing else.
Nursing
- Use of English
- Biology
- Chemistry
- Physics
Yes, Nursing uses the same combination as Medicine in most universities.
Pharmacy
- Use of English
- Biology
- Chemistry
- Physics
Medical Laboratory Science
- Use of English
- Biology
- Chemistry
- Physics
Physiology / Anatomy
- Use of English
- Biology
- Chemistry
- Physics or Mathematics
Public Health
- Use of English
- Biology
- Chemistry
- Physics or Mathematics
Note:
If you’re aiming for any medical course and you did not offer Physics, Chemistry, and Biology, you should strongly consider a change of course.
JAMB Subject Combinations for Engineering Courses
Engineering courses are also strict, especially about Mathematics and Physics.
Common Engineering Combinations
For almost all engineering courses:
- Use of English
- Mathematics
- Physics
- Chemistry
This applies to:
- Civil Engineering
- Mechanical Engineering
- Electrical/Electronics Engineering
- Chemical Engineering
- Petroleum Engineering
- Computer Engineering
No Mathematics = no Engineering.
No Physics = no Engineering.
JAMB Subject Combinations for Science Courses
Computer Science
- Use of English
- Mathematics
- Physics
- Biology or Chemistry
Some schools allow Economics instead of Biology/Chemistry, but Physics and Mathematics are usually compulsory.
Biochemistry
- Use of English
- Biology
- Chemistry
- Physics or Mathematics
Microbiology
- Use of English
- Biology
- Chemistry
- Physics or Mathematics
Physics
- Use of English
- Physics
- Mathematics
- Chemistry or Biology
Chemistry
- Use of English
- Chemistry
- Physics
- Mathematics or Biology
Mathematics
- Use of English
- Mathematics
- Physics
- Chemistry or Economics
JAMB Subject Combinations for Business & Management Courses
These courses are more flexible but still follow a pattern.
Accounting
- Use of English
- Mathematics
- Economics
- One other social science or commercial subject
Business Administration
- Use of English
- Mathematics
- Economics
- Government or Commerce
Banking and Finance
- Use of English
- Mathematics
- Economics
- One other relevant subject
Marketing
- Use of English
- Mathematics
- Economics
- Government or Commerce
My honest advice:
If you’re going into business, Economics is almost mandatory. Skipping it is risky.
JAMB Subject Combinations for Arts Courses
Arts courses allow more flexibility, but you still need to be smart.
Law
- Use of English
- Literature in English
- Any two other Arts or Social Science subjects
English Language
- Use of English
- Literature in English
- Two other Arts subjects
History and International Studies
- Use of English
- History or Government
- Two other Arts subjects
Religious Studies (CRS/IRS)
- Use of English
- CRS or IRS
- Two other Arts subjects
JAMB Subject Combinations for Social Science Courses
Political Science
- Use of English
- Government or History
- Two other Social Science or Arts subjects
Economics
- Use of English
- Mathematics
- Economics
- Government or Geography
Sociology
- Use of English
- Government
- Economics
- One other relevant subject
Psychology
- Use of English
- Biology
- Government
- One other relevant subject
JAMB Subject Combinations for Agricultural Courses
Agriculture
- Use of English
- Chemistry
- Biology or Agricultural Science
- Mathematics or Physics
Agricultural Economics
- Use of English
- Chemistry
- Biology or Agricultural Science
- Mathematics
Common JAMB Subject Combinations Mistakes Students Make
Let’s talk about mistakes, because avoiding them is just as important.
1. Copying Friends
Your friend’s course is not your course. Simple.
2. Assuming WAEC Subjects Automatically Work
WAEC and JAMB are related, but not identical in requirements.
3. Ignoring School-Specific Rules
Some universities are stricter than others.
4. Not Checking the JAMB Brochure
The brochure exists for a reason. Use it.
Read also: Top 13 Mistakes to Avoid in JAMB 2026 UTME (and How to Score 300+)
How to Confirm Your JAMB Subject Combinations Before Submitting
Before you click “submit,” do this:
- Check the JAMB brochure
- Check at least two universities offering your course
- Confirm from a reliable education platform
- Ask questions if unsure, don’t guess
Ten minutes of checking can save one full year.
Final Thoughts: Don’t Let One Mistake Ruin Your Admission
Your JAMB subject combinations is not just a formality.
It is a decision that can determine whether you gain admission or not, regardless of how intelligent or hardworking you are.
If you’ve read this far, you’re already ahead of many candidates.
Take your time. Choose wisely. And when in doubt, always verify.
If you found this guide helpful, share it with someone preparing for JAMB. You might be saving them from a costly mistake.

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